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November 25, 2015
10:00 EDTIMGNOn The Fly: Analyst Upgrade Summary
Today's noteworthy upgrades include: Actelion (ALIOY) upgraded to Neutral from Sell at Citi... Alliance Data (ADS) assumed with an Overweight from Neutral at Piper Jaffray... BG Group (BRGYY) upgraded to Outperform from Sector Perform at RBC Capital... Cubic (CUB) upgraded to Buy from Hold at Benchmark... Frontline (FRO) upgraded to Neutral from Underperform at Credit Suisse... Hormel Foods (HRL) upgraded to Overweight at Stephens... ImmunoGen (IMGN) assumed with a Buy from Hold at Jefferies... Metro (MTTRY) upgraded to Buy from Hold at Jefferies... Palo Alto (PANW) upgraded to Buy from Hold at Argus... Pfizer (PFE) upgraded to Neutral from Reduce at SunTrust... Tech Data (TECD) upgraded to Market Perform from Underperform at Raymond James.
06:26 EDTIMGNImmunoGen assumed with a Buy from Hold at Jefferies
Jefferies analyst Biren Amin upgraded ImmunoGen to Buy after assuming coverage of the name. Mirvetuximab has shown "robust activity" in patients with ovarian cancer that are highly expressing the folate receptor, and data from an additional 40 patients in Q2 of 2016 could be the next catalyst for the stock, Amin tells investors in a research note. He doubled his price target for ImmunoGen shares to $16 from $8.
November 24, 2015
12:59 EDTAEZSGEO Investing says Aeterna Zentaris rally 'totally unwarranted'
GEO Investing tweeted, "We believe $AEZS pump is totally unwarranted and that stock will quickly follow if $KBIO sells off."
11:30 EDTAEZSAeterna Zentaris says no corporate developments to account for stock movement
Aeterna Zentaris, at the request of IIROC on behalf of the Toronto Stock Exchange, confirms that as of the date of this news release there are no corporate developments that would cause the recent movements in the company's share price.
November 20, 2015
08:32 EDTMDASMedAssets extends strategic partnership with HealthTechS3
MedAssets announced an extension of its long-standing strategic partnership with HealthTechS3, or HTS3, a Brentwood, Tenn.-based provider of financial services, executive/physician recruitment, consulting/management services and supply chain solutions to critical access and acute care hospitals in rural areas and smaller communities across the United States. The agreement continues a successful 20-year participation in HTS3's Business Partnership Program, through which HTS3 customers can access MedAssets' supply chain and capital and construction solutions to reduce the total cost of care. Through this ongoing relationship, MedAssets offers the pricing advantages of its contracted supplies, purchased services and capital equipment, as well as tools and field expertise to gain greater fiscal control of the construction and renovation process.
November 19, 2015
08:32 EDTAEZSAeterna Zentaris enrolls first patient for Phase 3 trial of Macrilen
Aeterna Zentaris has enrolled the first patient for its confirmatory Phase 3 clinical study to demonstrate the efficacy of Macrilen, a novel orally-active ghrelin agonist for use in evaluating adult growth hormone deficiency. Based on meetings with the FDA as well as the EMA and subsequent written scientific advice, the company believes that the study meets the FDA's and the EMA's study-design expectations allowing US and European approval, if successful.
November 18, 2015
08:34 EDTAEZSAeterna Zentaris announces share consolidation details for NASDAQ compliance
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November 17, 2015
06:26 EDTMDASThe Advisory Board initiated with an Overweight at JPMorgan
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November 16, 2015
17:16 EDTAMEDNorth Tide Capital reports 8.1% passive stake in Amedisys
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14:07 EDTIMGNClovis plunges after lung cancer drug response rate misses expectations
Shares of Clovis Oncology (CLVS) plunged more than 70% after the drugmaker reported new details regarding its cancer drug candidate rociletinib, with new, confirmed data showing an unexpected drop in effectiveness. SURPRISING DRUG RESULTS: Clovis announced this morning new details regarding its rociletinib drug, which is being studied for the treatment of non-small cell lung cancer. According to the company, the Food and Drug Administration is now requesting additional clinical data on the drug, with a renewed focus on so-called confirmed treatment responses. Clovis explained that previous applications submitted to the FDA -- as well as early data on the drug publicized at medical conferences and elsewhere -- contained some immature and unconfirmed results. Perhaps most notably, the company disclosed that "as the efficacy data have matured, the number of patients with an unconfirmed response who converted to a confirmed response was lower than expected," with the current confirmed response rate for rociletinib now standing at 28% for the 500mg dose and 34% for the 625mg group. The primary driver of the low conversion to confirmed responses was due to ineffective tumor shrinkage as well as general disease progression, including brain metastasis, said the company. APPROVAL DELAY: In the wake of this morning's update, Piper Jaffray's Charles Duncan cut his price target on Clovis shares to $28 from $92 while reiterating a Neutral rating. Duncan explained that Clovis had previously reported a 54%-60% unconfirmed response rate for rociletinib, a significant change from today's confirmed numbers. The analyst had previously speculated that rociletinib might further differentiate itself in the market by demonstrating a meaningful impact on brain metastasis, but Monday's commentary from Clovis seems to specifically downplay that possibility. Though the new data "may still ultimately be approvable," Duncan envisions an approval delay of three to six months given what was revealed, and he pushed anticipated first U.S. sales of the drug to the fourth quarter of 2016 while cutting his expected second-line market penetration to just 25% from 45%. RETHINKING CLOVIS: Goldman Sachs analyst Terence Flynn said he views the news as a "significant setback" for rociletinib, especially given that the updated responses rates come in below that of Tagrisso, AstraZeneca's (AZN) recently-approved rival treatment option. As a result, Flynn put his Conviction Buy rating and $123 price target on Clovis "under review." IMMUNOGEN PRESSURED: Weighing in on the news, RBC's Simos Simeonidis speculated that Monday's selloff in ImmunoGen (IMGN) shares could be related to the Clovis update, as investors may be drawing a parallel between the company's IMGN853 and rociletinib. IMGN853 saw a similar drop in efficacy when adjusting data for confirmed responses, but the drug looks outright potent when limiting results to just key patient groups, the analyst contended. Though IMGN853 will still have to prove itself in larger trials, Simeonidis nevertheless sees the current weakness in ImmunoGen as a buying opportunity. PRICE ACTION: Shares of Clovis have dived more than $71, or 71.5%, to $28.35 in afternoon trading, while ImmunoGen has fallen 7% to $11.62. AstraZeneca, meanwhile, is up better than 4%.
12:21 EDTIMGNImmunoGen selloff on Clovis news unwarranted, says RBC Capital
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11:52 EDTAEZSAeterna Zentaris announces shareholder approval of 100-for-1 share consolidation
Aeterna Zentaris announced that the holders of its issued and outstanding common shares approved a share consolidation and that the company has determined that the consolidation ratio will be 100-for-1. The company intends to implement the consolidation in the coming days and will shortly provide all relevant details regarding the consolidation, including its effective date and the date on which the common shares are expected to commence trading on a post-consolidation basis on the NASDAQ Capital Market and the Toronto Stock Exchange and information for registered and beneficial shareholders to exchange their pre-consolidation for post-consolidation common shares. The company also announces that Marcel Aubut is no longer a member of the Board of Directors effective November 16.
November 13, 2015
10:17 EDTAEZSAeterna Zentaris to host special shareholder meeting
Special shareholder meeting to be held on November 16 at 9:30 am.
07:40 EDTDSCIDerma Sciences price target lowered to $8 from $17 at Oppenheimer
Oppenheimer cut its price target on Derma after the company announced the termination of its Phase III aclerastide diabetic foot ulcer study due to negative data indications. However, the firm expects the company's sales to grow by high single digit percentage levels in 2016, and it keeps an Outperform rating.
November 12, 2015
19:11 EDTCRVLCorVel expands repurchase plan by 1M shares
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16:27 EDTDSCIOn The Fly: Top stock stories for Thursday
Stocks on Wall Street opened in negative territory and weakened throughout the day, pushing equities down to their lowest levels of November. Comments made by Fed officials early in the day lent more uncertainty, not more clarity, regarding the chances of a rate hike at the FOMC meeting in December. The commodity sector was also weak, led by oil, which saw benchmark U.S. prices hit a three month low as WTI crude slid below $42 per barrel. ECONOMIC EVENTS: In the U.S., initial jobless claims were unchanged at 276,000 in the week of November 7, versus expectations for 270,000 first-time claims. The JOLTS report showed job openings rebounded 149,000 to 5.53M in September. In Europe, European Central Bank president Mario Draghi, in remarks delivered in a hearing in the European Parliament, once again signaled that the bank is ready to boost stimulus at its December meeting, if warranted. COMPANY NEWS: Shares of Angie's List (ANGI) gained $1.05, or 13.26%, to $8.97 after IAC/InterActiveCorp (IACI), the parent company of HomeAdvisor, made public a $8.75 per share cash buyout offer. Yelp (YELP), which also connects people with local businesses via its web-based and mobile services, rose 92c, or 3.66%, to $25.90 following the revelation of the takeout bid for Angie's List... Department store owner Kohl's (KSS) advanced $2.64, or 6.12%, to $45.80 after its third quarter earnings and revenues beat expectations... Shares of PayPal (PYPL) were weak for a second straight session following a report yesterday afternoon alleging that Apple (AAPL) is set to launch a competitor to one of the payment technology company's offerings. Shares of PayPal slipped 1.8% to close at $36.33 yesterday following The Wall Street Journal's report, then dipped another 2.1% to close at $35.57 today. MAJOR MOVERS: Among the notable gainers was Eros International (EROS), which rebounded 65c, or 7.88%, to $8.90 after calling allegations of security laws violations "baseless and misleading." Also higher was Splunk (SPLK), which rose $1.61, or 2.82%, to $58.78 after research firm JMP Securities reiterated an Outperform rating on the name, saying recent checks indicate that spending on Splunk products "remains healthy." (JD) advanced 3.2% to $28.78 after reporting 130% sales growth for China's Singles Day event. Among the noteworthy losers was Fairmount Santrol (FMSA), which fell 66c, or 22%, to $2.34 after reporting downbeat third quarter earnings and suspending its earnings guidance due to market "uncertainty." Also lower was Advance Auto Parts (AAP), which declined $30.00, or 15.41%, to $164.67 after its quarterly report missed analyst expectations, which came alongside a retirement announcement by its CEO and news of Starboard chief Jeff Smith being appointed to the company's board. Additionally, Derma Sciences (DSCI) lost 27.9% to $4.04 after terminating its Phase 3 clinical trials of aclerastide for the treatment of foot ulcers due to futility. INDEXES: The Dow fell 254.15, or 1.44%, to 17,448.07, the Nasdaq lost 61.94, or 1.22%, to 5,005.08, and the S&P 500 dropped 29.03, or 1.4%, to 2,045.97.
09:21 EDTDSCIOn The Fly: Pre-market Movers
UP AFTER EARNINGS: Kohl's (KSS), up 5.4%... NetEase (NTES), up 6.3%... SunPower (SPWR), up 3.4%. ALSO HIGHER: Angie's List (ANGI), up 12.1% after after IAC (IAC) proposes to acquire the company... OHR Pharmaceutical (OHRP), up 7.4% after submitting a Special Protocol Assessment request to the FDA for OHR-102... Galena Biopharma (GALE) up 6.2% after being upgraded to Outperform from Perform at Oppenheimer... MannKind (MNKD), up 5.4% after confirming a planned stock sale. DOWN AFTER EARNINGS: Freshpet (FRPT), down 25%... Advance Auto Parts (AAP), down 11.1%... Viacom (VIAB), down marginally. ALSO LOWER: Derma Sciences (DSCI), down 30.4% after ending its Phase 3 clinical trials with aclerastide, DSC127, for diabetic foot ulcer healing... Sunedison (SUNE), down 11.2% after being downgraded to Sell from Neutral at Axiom.
08:06 EDTDSCIDerma Sciences to hold a conference call
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07:31 EDTDSCIDerma Sciences ending Phase 3 studies based on recommendation by DMC
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07:31 EDTDSCIDerma Sciences announces termination of Phase 3 trials with aclerastide
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