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November 4, 2012
11:34 EDTALXNAlexion:Data show long-term benefits of chronic Soliris therapy in aHUS patients
Alexion Pharmaceuticals announced the presentation of two-year data that highlight the long-term benefits of chronic Soliris, eculizumab, therapy in patients with atypical hemolytic uremic syndrome, aHUS, an ultra-rare genetic disease characterized by thrombotic microangiopathy, TMA, the formation of blood clots in small blood vessels throughout the body. In two pivotal phase 2 studies, which initially enrolled 37 patients, 32 patients entered a long-term extension phase. The data demonstrated that ongoing Soliris treatment for two years was associated with sustained inhibition of complement-mediated TMA, as indicated by a maintained increase in platelet count, and sustained improvement in renal function and TMA event-free status.1,2 The data were presented today at Kidney Week 2012, the annual meeting of the American Society of Nephrology, ASN, in San Diego. Additionally, data presented in a poster session at ASN support early initiation of Soliris therapy regardless of the presence or absence of genetic mutations in patients with aHUS.
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July 25, 2014
07:44 EDTALXNAlexion valuation looking increasingly compelling, says Stifel
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July 24, 2014
11:53 EDTALXNAlexion price target raised to $214 from $196 at Piper Jaffray
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06:43 EDTALXNAlexion raises 2014 adjusted EPS view to $4.95-$5.05 from $4.75-$4.85
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06:41 EDTALXNAlexion reports Q2 adjusted EPS $1.12, consensus $1.07
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06:17 EDTALXNAlexion's hypophosphatasia candidate MAA accepted by European Medicines Agency
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July 22, 2014
11:48 EDTALXNStocks with call strike movement; EXPE ALXN
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