New User:

-or-
Username:
Password:
Forgot your password?

Stock Market & Financial Investment News

News Breaks
March 18, 2013
08:05 EDTALNYAlnylam initiates phase I study for subcutaneously delivered RNAi therapeutic
Alnylam Pharmaceuticals announced that it has initiated dosing in its Phase I clinical trial with ALN-TTRsc, an RNAi therapeutic targeting transthyretin for the treatment of TTR-mediated amyloidosis. The Phase I trial of ALN-TTRsc is being conducted in the U.K. as a randomized, double-blind, placebo-controlled, single- and multi-dose, dose-escalation study, enrolling up to 40 healthy volunteer subjects. The primary objective of the study is to evaluate the safety and tolerability of single and multiple doses of subcutaneously administered ALN-TTRsc. Secondary objectives include assessment of clinical activity of the drug as measured by serum TTR levels. Alnylam expects to present data from this trial in mid-2013. Upon completion of the Phase I trial, the company plans to start a Phase II clinical study of ALN-TTRsc in FAC patients by the end of 2013 and, assuming positive results, expects to start a pivotal trial for ALN-TTRsc in FAC patients in 2014.
News For ALNY From The Last 14 Days
Sign up for a free trial to see the rest of the stories you've been missing.
December 24, 2014
07:50 EDTALNYAlnylam price target raised to $106 from $90 at JPMorgan
Subscribe for More Information
December 19, 2014
08:01 EDTALNYAlnylam announces planned departure of Chief Business Officer
Subscribe for More Information
December 18, 2014
08:09 EDTALNYAlnylam names Cubist CEO Michael Bonney to board of directors
Subscribe for More Information
December 15, 2014
08:42 EDTALNYAlnylam price target raised to $125 from $105 at Leerink
Subscribe for More Information
06:06 EDTALNYAlnylam price target raised to $158 from $134 at Piper Jaffray
Subscribe for More Information

Sign up for a free trial to see the rest of the stories you've been missing.

I agree to the theflyonthewall.com disclaimer & terms of use