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News Breaks
April 7, 2014
08:09 EDTMRK, ALNYAlnylam's McSwiggen patent upheld in European opposition proceedings
Alnylam (ALNY) announced that the European Patent Office has upheld the McSwiggen EP 1423406 patent in oral opposition proceedings in Munich, Germany. The McSwiggen patent estate describes chemical modifications of RNAi therapeutics that the company believes are critical for achieving “drug-like” properties in siRNA, the molecules that mediate RNAi. The patent is owned by Alnylam, and was recently obtained through the company’s acquisition of Sirna Therapeutics from Merck (MRK). The McSwiggen patent family comprises a core component of Alnylam’s overall intellectual property estate for the advancement of RNAi therapeutics as a new class of medicines.
News For ALNY;MRK From The Last 14 Days
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April 15, 2015
08:33 EDTMRKFDA panel results positive for Merck, says SunTrust
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April 14, 2015
13:32 EDTMRKMerck, NewLink Genetics confirm initiation of Phase 3 trial of Ebola vaccine
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08:18 EDTALNYAlnylam data encouraging, says JMP Securities
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April 13, 2015
11:02 EDTALNYAlnylam publishes pre-clinical results on ALN-AT3
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10:15 EDTALNYHigh option volume stocks
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08:58 EDTMRKMerck may have positive read through from briefing docs, says SunTrust
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April 9, 2015
09:25 EDTMRKPiper Jaffray pharmaceuticals analysts hold an analyst/industry conference call
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April 8, 2015
07:33 EDTMRKAdvaxis, Merck begin enrollment in Phase 1/2 of ADJX-PSA with Keytruda
Advaxis (ADXS) and Merck (MRK) announced that enrollment has initiated in the Phase 1/2 clinical trial evaluating the combination of ADXS-PSA, an investigational Lm-LLO immunotherapy, and Keytruda, the first anti-PD-1 therapy approved in the United States, in patients with previously treated, metastatic castration-resistant prostate cancer, or mCRPC. The clinical trial, KEYNOTE-046, is the first-in-human study of Advaxis's lead Lm-LLO immunotherapy candidate for prostate cancer. It is the second study initiated to evaluate the use of KEYTRUDA in the treatment of advanced prostate cancer. ADXS-PSA and KEYTRUDA are members of a class of cancer treatments known as immuno-oncology therapies. Data from preclinical studies suggest that Advaxis Lm-LLO immunotherapies in combination with a PD-1 antibody may lead to an enhanced anti-tumor immune response. The results from KEYNOTE-046 will determine the future clinical development program for the combination.
07:04 EDTMRKMerck's investigational Hep C therapy granted breakthrough therapy designations
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06:57 EDTALNYAlnylam added to short-term buy list at Deutsche Bank
April 7, 2015
07:14 EDTMRKEyeforpharma to hold a summit
Philadelphia 2015 Commercial Pharma Summit is being held in Philadelphia on April 7-8.

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