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August 8, 2014
08:56 EDTADHDAlcobra releases results from MRI study to evaluate effects of MDX
Alcobra released topline results from a pharmacological MRI study designed to evaluate the regions of the brain that are modulated by MDX. The study evaluated brain response to a single administration of Metadoxine in rats. The results showed that Metadoxine produced a significant, dose-dependent decrease in BOLD signal in highly selective regions of the brain including the prefrontal cortex and showed a statistically significant increase in BOLD response in brain regions including the central nucleus of the amygdala and the lateral hypothalamus. In addition, none of the mesolimbic dopamine system brain regions , known to be involved in the reinforcing effects of scheduled drugs, were significantly affected by Metadoxine at any dose level, which is consistent with previously presented data.
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September 23, 2014
10:37 EDTADHDAlcobra October volatility elevated into Phase III trial data
Alcobra October call option implied volatility is at 347, November is at 249, December is at 223; compared to its 15-week average of 191 according to Track Data, suggesting large price movement into release of data from the first Phase III trial of MDX in Adult ADHD.
September 22, 2014
07:12 EDTADHDAlcobra October volatility elevated into Phase III trial data
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September 19, 2014
16:24 EDTADHDAlcobra announces completion of all patient visits in phase 3 MDX trial
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September 12, 2014
11:03 EDTADHDOptions with increasing implied volatility
Options with increasing implied volatility: ADHD VNET AVNO RAX VALE NLY EWZ BBBY SYY GGP
September 10, 2014
11:23 EDTADHDOptions with increasing implied volatility
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September 9, 2014
12:08 EDTADHDOptions with increasing implied volatility
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